diff --git a/README.md b/README.md
new file mode 100644
index 0000000000000000000000000000000000000000..646ed6165a25f733bc701754a0faa4cd4d301fc3
--- /dev/null
+++ b/README.md
@@ -0,0 +1,7 @@
+Matlab files to reproduce the results of the manuscript "Mechanisms of a sustained anti-inflammatory drug response in alveolar macrophages unraveled with mathematical modeling" by Nyman et al. The IQM toolbox is used. 
+
+First, you need to install the toolbox from https://iqmtools.intiquan.com/
+
+Second, run the file initIQM.m
+
+To reproduce the results in the manuscript, run plot_many_params.m for each hypothesis
\ No newline at end of file