From 57be64f0583f0a32f46f4d4f53a8fdc218866e41 Mon Sep 17 00:00:00 2001 From: Elin Nyman <elin.nyman@liu.se> Date: Wed, 5 Feb 2020 12:26:02 +0100 Subject: [PATCH] Update README.md --- README.md | 22 +++++++++++++++++++--- 1 file changed, 19 insertions(+), 3 deletions(-) diff --git a/README.md b/README.md index 646ed61..0a2f987 100644 --- a/README.md +++ b/README.md @@ -1,7 +1,23 @@ -Matlab files to reproduce the results of the manuscript "Mechanisms of a sustained anti-inflammatory drug response in alveolar macrophages unraveled with mathematical modeling" by Nyman et al. The IQM toolbox is used. +Matlab files to reproduce the results of the manuscript **Mechanisms of a sustained anti-inflammatory drug response in alveolar macrophages unraveled with mathematical modeling** by Nyman et al. + +The IQM toolbox is used. First, you need to install the toolbox from https://iqmtools.intiquan.com/ -Second, run the file initIQM.m +Second, run the file `initIQM.m` + +To reproduce the results in the manuscript, run `plot_many_params.m` for each hypothesis + +The included files: + +`macrophage_simple.txt` model text file in the format of the IQM toolbox + +`allGoodValuesX.dat` contains acceptable parameter values + +`cost_simple.m` computes the cost and need a set of parameter values as input + +`LoadData.m` computes mean values and standard error of the means from the raw data with only LPS stimulation and load to workspace + +`LoadDrugData.m` computes mean values and standard error of the means from the raw data with addition of Dexamathasone and load to workspace -To reproduce the results in the manuscript, run plot_many_params.m for each hypothesis \ No newline at end of file +`` \ No newline at end of file -- GitLab